Menopur & Trigger Shot Calculator

Mixing the vials into a small amount of saline makes a solution with a known concentration. Dividing your dose by that concentration tells you how much liquid holds your dose.

Concentration (IU/mL) = vials × 75 ÷ saline (mL)
Draw (mL) = dose (IU) ÷ concentration (IU/mL)
Syringe units = draw (mL) × 100

Example: 225 IU needs 3 vials (225 IU). In 1 mL of saline that is 225 IU/mL, so 225 IU is 1 mL, which reads 100 units on a U-100 syringe. The label calls for using the liquid from the first vial to dissolve the rest, so the total liquid stays small.

The powder adds a tiny bit of volume, so the true concentration is a little lower than this math says. That is why, when your dose uses every vial you mixed, you draw up all of the liquid instead of trusting the line on the syringe.

Concentration (IU/mL) = vial strength (IU) ÷ diluent (mL)
Draw (mL) = dose (IU) ÷ concentration (IU/mL)
Syringe units = draw (mL) × 100

Example: a 10,000 IU vial mixed with 1 mL is 10,000 IU/mL. A 5,000 IU dose is 0.5 mL, which reads 50 units on a U-100 syringe. The same vial mixed with 10 mL is 1,000 IU/mL, and 5,000 IU becomes 5 mL. The dose is identical; the volume is ten times larger. That is why the diluent amount matters so much.

After mixing, hCG goes in the refrigerator. Check your product’s label for how long it keeps (the Novarel label says 30 days; the Pregnyl label says 60 days).

Draw (mL) = dose (mg) ÷ 5
Syringe units = draw (mL) × 100 = dose (mg) × 20

Example: 2 mg ÷ 5 mg/mL = 0.4 mL = 40 units. And if your instructions say “40 units,” the same math runs backward: 40 units ÷ 20 = 2 mg.